HIF-1α (Hypoxia-Inducible Factor-1α) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383
نویسندگان
چکیده
منابع مشابه
MiR-138 suppresses expression of hypoxia-inducible factor 1α (HIF-1α) in clear cell renal cell carcinoma 786-O cells.
OBJECTIVES Hypoxia-inducible factor-1alpha (HIF-1a) is widely considered to be one of the key regulators in cancer cells. Here, we investigated a microRNA regulating expression of HIF-1a and explored its functions in clear cell renal cell carcinoma (ccRCC) cells. METHODS AND MATERIALS Western blot and reporter assays were used to assess HIF-1a as a direct target of miR-138. The effects of miR...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2020
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.119.313290